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Smoothing, Firming & Brightening Creme with STEM CELLS

Our Price: $81.00


Product Description How to Use Ingredients
A safe, effective anti-aging and skin-lightening agent that helps with anti-oxidation, collagen formation, the inhibition of discoloration in any area that is dull, mottled, or displaying fine lines (ie: under-eye and eyelid area, nasal labial folds, upper lip, chin, neck and hands)!  

With continuous use of this product, you’ll see changes in the contours and colors of the face, neck and chest, giving your skin a plumper, smoother and brighter appearance.  Smoothing, Firming & Brightening Crème with Acetyl Hexapeptide-8 (aka: Argireline) takes 5-7 weeks to work.  Use morning and evening on any area that needs extra work!

The clinical results on the trails for this ingredient are amazing!  Results are seen almost instantaneously and dramatically!  Argireline offers superior anti-wrinkle efficacy: Studies demonstrate that it is highly efficacious at not only inhibiting wrinkle development but in reducing existing wrinkle depth as well.  Facial wrinkly associate with aging is caused and exacerbated by many factors.  Beyond the physiological pathways, molecular mechanisms involved in facial aging include changes in collagen conformation, elastin polypeptide degradation and problems of the skin’s lipid matrix.   Recent studies clearly establish that these changes can be significantly reduced by inhibiting SNARE complex formation, a core of membrane proteins that mediate neuronal exocytosis.  Their inhibitions by short synthetic peptides can decrease facial wrinkles.

In vivo tests further demonstrated the benefits of Argireline solution.  Facial topography analysis (for measuring the effectiveness of an O/W emulsion containing 10% Argireline solution) was performed using silicon replicas from around the eyes at 0, 15, and 30 days of a twice-a-day treatment regimen.  Analyses of the imprints were performed by confocal laser scanning microscopy.  It was observed that the severity of wrinkles around the eyes decreased up to 17% after 15 days of treatment and up to 27% after 30 days of treatment, substantiating the proposed biochemical mechanism hypothesis.  Argireline solution was ascertained in two different vitro tests directly related to the formation of wrinkles in the epidermis as well as a separate in vivo test performed on healthy human volunteers

Average Customer Review: 5 of 5 Total Reviews: 6 Write a review.

  0 of 0 people found the following review helpful:
It's pretty amazing... June 21, 2016
Reviewer: Christine B. from NYC, NY  
I've just recently gone back to using Sage's Smoothing, Firming & Brightening Creme and realize I'd forgotten how much I loved it. In the past, I felt that it made my skin too shiny, despite its effectiveness in evening out my skin tone. No shininess this time around, however. It's pretty amazing stuff.

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  0 of 1 people found the following review helpful:
Great stuff May 24, 2016
Reviewer: Susie Hochman from Clayton, MO United States  
I ordered and received my SF&B creme within 3 days. Very pleased with that.

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  0 of 0 people found the following review helpful:
Geat product - Leaves my skin very smooth! April 29, 2016
Reviewer: Kelly from Chicago, IL United States  
I use the Smoothing, Firming & Brightening creme in the morning, after Facial Shampoo and Eye & Lip Balm.  Later, when I wash my face at night, I can’t believe how smooth my skin feels!  I’ve been using Sage products for over 15 years, and I get lots of compliments on my skin!

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  0 of 0 people found the following review helpful:
Love this new Sage Product February 6, 2016
Reviewer: christine camp from st louis, MO United States  
I have been using Sage products for over 20 years and love the results.  Turning 60 this year with no wrinkles is amazing!  I have always used Sage Smoothing Firming and Brightening Creme.  Recently Sage added Stem Cells.  That's why I love Sage.  Barbara is always improving and adding to make her products the best.  We are blessed to have her in St. Louis, MO.  XO to Barbara

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  0 of 1 people found the following review helpful:
Trtid the first tube October 5, 2015
Reviewer: Sudarshana Ghosh from New York, NY United States  
this time the consistency was good.

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